Toxicological effects of personal exposure to fine particles

Many studies have reported the association between fine particles and the increased incidence of respiratory and pulmonary diseases. However, few of them investigated the toxicological effects of source-specific particles at the individual level. This study provided the first detailed source-exposure-toxicity data for Hong Kong. It measured the cytotoxicity, inflammatory response and reactive oxygen species production in terms of personal exposure. The analysis is suitable for designing source-targeted mitigation strategies such as implementing traffic emissions control to reduce elemental carbon exposure. (Environ Pollut. 2021 Feb 3;275:116633. doi: 10.1016/j.envpol.2021.116633. Online ahead of print.)

Anyone interested in future collaboration in this field of research is welcome to contact our key investigator Prof KF HO in The Jockey Club School of Public Health and Primary Care, CUHK. Prof Ho’s research focuses on indoor or outdoor air pollution and health, particle toxicology, exposure assessment and bio-aerosol.