中大職務
- 醫學院副院長 (研究)
- 化學病理學系系主任
- 李嘉誠醫學講座教授
- 化學病理學講座教授
- 李嘉誠健康科學研究所所長
- 轉化腫瘤學國家重點實驗室（香港中文大學）主任
專業範疇
- 基因與醫學
- DNA測試及其他有關化學病理的範疇
教育及資歷
BA (Hons) (Cantab), BM BCh (Oxon), SBS MA (Cantab), DPhil (Oxon), DM (Oxon), FRCP (Lond), FRCP (Edin), FRCPath (UK)
專注研究
- 分子診斷
- 無創傷性產前診斷
- 癌症生物標誌物
更多資訊
獎項及榮譽
- 拉斯克獎 — 臨床醫學研究得獎者, 2022
- 科學突破獎 – 生命科學得獎者, 2021
- 澳門大學榮譽理學博士
- Senior Fellow, PHG Foundation
- 英國皇家學會院士
- 美國國家科學院外籍院士
- 世界科學院院士
- 港科院創院院士
- 未來科學大獎－生命科學獎得獎者, 2016
- 費薩爾國王國際醫學獎得獎者, 2014
- 英國劍橋大學伊曼紐爾學院榮譽院士
- 湯森路透引文桂冠獎 - 化學
- 皇家婦產科學院榮譽院士
專業服務
- 香港科學院院長
- 香港科技創新聯盟主席
- 特首政策組專家組 — 研究策略專家組成員
部分論文 (只有英文版本)
- Lam WKJ, Jiang P, Chan KCA, Cheng SH, Zhang H, Peng W, Tse OYO, Tong YK, Gai W, Zee BCY, Ma BBY, Hui EP, Chan ATC, Woo JKS, Chiu RWK, Lo YMD (2018). Sequencing-based counting and size profiling of plasma Epstein-Barr virus DNA enhance population screening of nasopharyngeal carcinoma. Proc Natl Acad Sci USA 115(22), E5115-E5124.
- Sun K, Jiang P, Wong AIC, Cheng YKY, Cheng SH, Zhang H, Chan KCA, Leung TY, Chiu RWK, and Lo YMD (2018). Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing. Proc Natl Acad Sci USA 115(22), E5106-E5114.
- Tsang JCH, Vong JSL, Ji L, Poon LCY, Jiang P, Lui KO, Ni YB, To KF, Cheng YKY, Chiu RWK, Lo YMD (2017). Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics. Proc Natl Acad Sci USA 114(37): E7786-E7795.
- Chan KCA, Woo JKS, King A, Zee BCY, Lam WKJ, Chan SL, Chu SWI, Mak C, Tse IOL, Leung SYM, Chan G, Hui EP, Ma BBY, Chiu RWK, Leung SF, van Hasselt AC, Chan ATC, Lo YMD (2017). Analysis of Plasma Epstein-Barr Virus DNA to Screen for Nasopharyngeal Cancer. N Engl J Med 377(6):513-522.
- Chan KCA, Jiang P, Sun K, Cheng YKY, Tong YK, Cheng SH, Wong AIC, Hudecova I, Leung TY, Chiu RWK, Lo YMD (2016). Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends. Proc Natl Acad Sci USA 113(50):E8159-E8168.
- Sun K, Jiang P, Chan KCA, Wong J, Cheng YKY, Liang RHS, Chang WK, Ma ESK, Chan SL, Cheng SH, Chan RWY, Tong YK, Ng SSM, Wong RSM, Hui DSC, Leung TN, Leung TY, Lai PBS, Chiu RWK, Lo YMD (2015). Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments. Proc Natl Acad Sci USA112(40):E5503-E5512.
- Jiang P, Chan CWM, Chan KCA, Cheng SH, Wong J, Wong VWS, Wong GLH, Chan SL, Mok TSK, Chan HLY, Lai PBS, Chiu RWK, Lo YMD(2015). Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients. Proc Natl Acad Sci USA 112(11):E1317-E1325.
- Yu SCY, Chan KCA, Zheng YWL, Jiang P, Liao GJW, Sun H, Akolekar R, Leung TY, Go ATJI, van Vugt JMG, Minekawa R, Oudejans CBM, Nicolaides KH, Chiu RWK, Lo YMD (2014). Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing. Proc Natl Acad Sci USA 111(23):8583-8588.
- Lo YMD, Chan KCA, Sun H, Chen EZ, Jiang P, Lun FMF, Zheng YW, Leung TY, Lau TK, Cantor CR, Chiu RWK (2010). Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus. Sci Transl Med 2:61ra91.
- Lo YMD, Lun FMF, Chan KCA, Tsui NBY, Chong KC, Lau TK, Leung TY, Zee BC, Cantor CR, Chiu RWK (2007). Digital PCR for the molecular detection of fetal chromosomal aneuploidy. Proc Natl Acad Sci USA 104:13116-13121.