中大職務
- 醫學院助理院長 (研究)
- 內科及藥物治療學系副教授
- 張金菱治療柏金遜綜合症研究中心副主任
- 劉達泉華人腦衰退疾病科研中心副主任
李嘉誠健康科學研究所首席研究員
蔡永業腦神經科學研究所首席研究員
專業範疇
- 神經科學
教育及資歷
BMedSc (CUHK), MBChB (CUHK), PhD (UCL)
專注研究
- 神經退化疾病中的膠質血管異常和治療靶點
- 調節感官運動行為的神經迴路及因老化而引致的功能障礙
- 成像工具及技術開發
更多資訊
獎項及榮譽
- 亞洲青年科學家基金（生命科學）得獎者, 2023
- 香港內科醫學院達安輝教授講者, 2022
- 國家優秀青年科學基金（港澳）得獎學者, 2021
- 裘槎前瞻科研大獎, 2020
- Finalist, Eppendorf 與 Science 神經生物學獎, 2014
部分論文 (只有英文版本)
Researcher ID: http://www.webofscience.com/wos/author/record/I-7513-2016
- Principles of deep immunostaining techniques for 3D histology.
Yau CN, Lai HM, Lee K, Kwok AJ, Huang J, Ko H.
Cell Reports Methods. 2023 May 22;3:100458. - An optofluidic platform for interrogating chemosensory behavior and brainwide neural representation in larval zebrafish.
Sy SKH, Chan DCW, Chan RCH, Lyu J, Li Z, Wong KKY, Choi CHJ, Mok VCT, Lai HM, Randlett O, Hu Y, Ko H.
Nature Communications. 2023 Jan 14;14(1):227. - Antibody stabilization for thermally accelerated deep immunostaining.
Lai HM, Tang Y, Lau ZYH, Campbell RAA, Yau CN, Chan CCY, Chan DCW, Wong HKT, Yan LYC, Wu WKK, Wong SH, Kwok KW, Wing YK, Lam HHN, Ng HK, Mrsic-Flogel TD, Mok VCT, Chan JYK, Ko H.
Nature Methods. 2022 Sep 1; 19(9):1137-1146. - Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner.
Li Z, Chen X, Vong JSL, Zhao L, Huang J, Yan LYC, Ip B, Wing YK, Lai HM, Mok VCT, Ko H.
Communications Biology. 2021 Jun 2;4(1)656. - Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain.
Zhao L, Li Z, Vong JSL, Chen X, Lai HM, Yan LYC, Huang J, Sy SKH, Tian X, Huang Y, Chan HYE, So HC, Ng WL, Tang Y, Lin WJ, Mok VCT, Ko H.
Nature Communications. 2020 Sep 4;11(1):4413. - Refinement of learned skilled movement representation in motor cortex deep output layer.
Li Q*, Ko H*, Qian ZM, Yan LYC, Chan DCW, Arbuthnott GW, Ke Y, Yung WH.
Nature Communications. 2017 Jun 9; 8:15834. - Emergence of feature-specific connectivity in cortical microcircuits in the absence of visual experience.
Ko H, Mrsic-Flogel TD, Hofer SB.
Journal of Neuroscience. 2014 Jul 16:34(29):9812-9816. - The emergence of functional microcircuits in visual cortex.
Ko H, Cossell L, Baragli C, Antolik J, Clopath C, Hofer SB, Mrsic-Flogel TD.
Nature. 2013 Apr 4;496(7443):96-100. - Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex.
Hofer SB*, Ko H*, Pichler B, Vogelstein J, Ros H, Zeng H, Lein E, Lesica NA, Mrsic-Flogel TD.
Nature Neuroscience. 2011 Jul 17;14(8):1045-52. - Functional specificity of local synaptic connections in neocortical networks.
Ko H, Hofer SB, Pichler B, Buchanan KA, Sjöström PJ, Mrsic-Flogel TD.
Nature. 2011 May 5;473(7345):87-91.