Professor NG Siew Chien
Assistant Dean (Development)
Croucher Professor in Medical Sciences
Professor, Department of Medicine and Therapeutics
CUHK Employment
- Assistant Dean (Development), Faculty of Medicine
- Professor, Department of Medicine and Therapeutics
- Director, Microbiota I-Center (MagIC)
- Associate Director, Centre for Gut Microbiota Research
- New Cornerstone Investigator
Expertise
- Inflammatory Bowel Disease
- Fecal Microbiota Transplantation
- Colorectal Cancer
- Endoscopy
- Gut Microbiome
Education & Qualifications
MBBS (Lond), PhD (Lond), FRCP (Lond), FRCP (Edin), AGAF, FHKCP, FHKAM (Medicine)
Research Interests
- Epidemiology, genetics, pathogenesis, and treatment of IBD
- Role of Gut microbiota in health and disease
- Fecal microbiota transplantation and microbial therapeutics
Additional Information
Award & Honour
- Highly Cited Researchers by Clarivate in 2020, 2021, 2022, 2023, and 2024
- Bank of China Hong Kong Science and Technology Prize (Life and Health), Bank of China Hong Kong, 2024
- Foreign Member of Academia Europaea (Clinical & Veterinary Science Section), Academia Europaea, 2024
- New Cornerstone Investigator (Biological and Biomedical Sciences), New Cornerstone Science Foundation, 2023
- Deloitte Technology Fast Outstanding Female Entrepreneur Award, Deloitte Hong Kong, 2023
- High Flyer Innopreneur Award, Federation of Hong Kong Industries, 2023
- Higher Education Outstanding Scientific Research Output Award – First-class Award in Natural Sciences, Ministry of Education, 2020
- Joanna and David Sachar International Award and Visiting Professorship in IBD, Icahn School of Medicine, Mount Sinai, 2019
- Sir Francis Avery Jones Visiting Professorship and Award, St Mark’s Hospital, London, 2019
- Visiting Professor, Shanghai Medical College, Fudan University, China
- Sir David Todd Lectureship, Hong Kong College of Physicians, 2017
- Outstanding Fellow, Faculty of Medicine, The Chinese University of Hong Kong, 2017
- Young Investigator Award, American Gastroenterology Association, 2016
- Distinguished Research Paper Award for Young Investigators, Hong Kong College of Physicians in 2014, 2015 and 2016
- Exemplary Teaching Award, Faculty of Medicine, The Chinese University of Hong Kong in 2014, 2015 and 2016
- JGH Emerging Leader Lectureship Award, Asian-Pacific Association of Gastroenterology, 2014
Professional Service
- President, The Hong Kong Society of Gastroenterology
- Associate Editor, Gut
- Advisory Board, Cell Host & Microbe
- Board Member, Cell Genomics
- External Assessor, University of Malaya
- External Assessor, University of New South Wales
Academic Engagement in CUHK
- Mentor, MBChB Programme Global Physician-Leadership Stream (GPS)
Selected Publications
- J Zheng, Q Sun, M Zhang, C Liu, Q Su, L Zhang, Z Xu, W Lu, JYL Ching, W Tang, CP Cheung, AL Hamilton, AL Wilson O'Brien, SC Wei, CN Bernstein, DT Rubin, EB Chang, M Morrison, MA Kamm, FKL Chan, J Zhang, SC Ng. Noninvasive, microbiome-based diagnosis of inflammatory bowel disease.Nature Medicine.10, 2024.
- Q Su, OWH Wong, W Lu, Y Wan, L Zhang, W Xu, MKT Li, C Liu, CP Cheung, JYL Ching, PK Cheong, TF Leung, S Chan, P Leung, FKL Chan, SC Ng. Multikingdom and functional gut microbiota markers for autism spectrum disorder.Nature Microbiology. 09, 2024. 9(9):2344-2355.
- Q Su, RI Lau, Q Liu, MKT Li, JWY Mak, W Lu, ISF Lau, LHS Lau, GTY Yeung, CP Cheung, W Tang, C Liu, JYL Ching, PK Cheong, FKL Chan, SC Ng. The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome.Cell Host Microbe. 05, 2024. 32(5):651-660.e4.
- RI Lau, Q Su, ISF Lau, JYL Ching, MCS Wong, LHS Lau, HM Tun, CKP Mok, SWH Chau, YK Tse, CP Cheung, MKT Li, GTY Yeung, PK Cheong, FKL Chan, SC Ng. A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial. Lancet Infectious Diseases. 03, 2024;24(3):256-265.
- FKL Chan, MCS Wong, AT Chan, JE East, HM Chiu, GK Makharia, D Weller, CJ Ooi, J Limsrivilai, Y Saito, DV Hang, JD Emery, D Makmun, KC Wu, RAR Ali, and SC Ng, Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) Clinical Practice Guidelines on the Use of Non-Invasive Biomarkers for Diagnosis of Colorectal Neoplasia. 04, 2023. Gut: p. 15.
- SC Ng, ZL Xu, JWY Mak, KL Yang, Q Liu, T Zuo, W Tang, L Lau, RN Lui, SH Wong, YK Tse, AYL Li, K Cheung, JYL Ching, VWS Wong, APS Kong, RCW Ma, EYK Chow, SKH Wong, ICH Ho, PKS Chan, and FKL Chan, Microbiota Engraftment after Faecal Microbiota Transplantation in Obese Subjects with Type 2 Diabetes: A 24-Week, Double-Blind, Randomised Controlled Trial. 03, 2021. Gut p. 8
- F Zhang, T Zuo, YK Yeoh, FWT Cheng, Q Liu, W Tang, KCY Cheung, KL Yang, CP Cheung, CC Mo, MM Hui, FKL Chan, CK Li, PKS Chan, and SC Ng, Longitudinal Dynamics of Gut Bacteriome, Mycobiome and Virome after Fecal Microbiota Transplantation in Graft-Versus-Host Disease. 01, 2021.Nature Communications 12(1): p. 11
- J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh, A Hamilton, OB AW, JYL Ching, H Wei, K Yang, Z Xu, SH Wong, JWY Mak, JJY Sung, M Morrison, J Yu, MA Kamm, SC Ng, Elucidation of Proteus mirabilis as a Key Bacterium in Crohn's Disease Inflammation.Gastroenterology, 01, 2021. 160(1): p. 317-330.e11.
- SC Ng, HY Shi, N Hamidi, FE Underwood, W Tang, EI Benchimol, R Panaccione, S Ghosh, JCY Wu, FKL Chan, JJY Sung, and GG Kaplan, Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies.Lancet, 12, 2017. 390(10114): p. 2769-2778.
- SC Ng, W Tang, RW Leong, M Chen, Y Ko, C Studd, O Niewiadomski, S Bell, MA Kamm, HJ De Silva, A Kasturiratne, YU Senanayake, CJ Ooi, KL Ling, D Ong, KL Goh, I Hilmi, Q Ouyang, YF Wang, P Hu, Z Zhu, Z Zeng, K Wu, X Wang, B Xia, J Li, P Pisespongsa, S Manatsathit, S Aniwan, M Simadibrata, M Abdullah, SWC Tsang, TC Wong, AJ Hui, CM Chow, HH Yu, MF Li, KK Ng, J Ching, JCY Wu, FKL Chan, and JJY Sung, Environmental risk factors in inflammatory bowel disease: A population-based case-control study in Asia-Pacific.Gut, 07, 2015. 64(7): p. 1063-1071.