Professor Lin Zhixiu
Director, School of Chinese Medicine
CUHK Employment
- Director, School of Chinese Medicine
- Director, Hong Kong Institute of Integrative Medicine
- Fellow, Chung Chi College
Expertise
- Chinese medicine clinical practice
- Pharmacology in Chinese medicines
- Clinical research on Chinese medicine
Education & Qualifications
BSc (TCM, Guangzhou); PhD (Pharmacognosy, King’s College London); Registered Chinese Medicine Practitioner, Chinese Medicine Council of Hong Kong
Research Interests
- Research and development of Chinese medicines for the treatment of common diseases
- Clinical trials to evaluate the effectiveness and safety of Chinese medical interventions for common medical conditions
- Phytochemistry of Chinese medicines
- Systematic reviews and meta-analysis
Additional Information
Professional Service
- Member, Working Group on Review of Safety Limits of Harmful Residues in Chinese Herbal Medicines, Department of Health, HKSAR
- President, Hong Kong Association of the Integrated Chinese and Western Medicine
- Chairman, Health Committee of The Chinese Medicine Practitioners Board, The Chinese Medicine Council of Hong Kong
- Member, Grant Review Board, Health and Medical Research Fund (HMRF), Health Bureau, HKSAR
- Founding President, Hong Kong Association of Chinese Herbal Pharmacology
- Vice President, Hong Kong Registered Chinese Medicine Practitioners Association
Academic Engagement in CUHK
- Programme Director, MSc in Chinese Medicine, School of Chinese Medicine
- Member, Faculty Student Disciplinary Committee
- Member, Management Board of the Institute of Biotechnology
- Member, Management Committee of Li Dak Sum Yip Chin R&D Centre for Chinese Medicine
- Member, Management Committee, Institute of Chinese Medicine
- College Co-ordinator, Chung Chi College
Selected Publications
- Zhang J, Xu HX, Cho WCS, Cheuk W, Li Y, Huang QH, Yang W, Xian YF*, Lin ZX*. Brucein D Augments the Chemosensitivity of Gemcitabine in Pancreatic Cancer via inhibiting the Nrf2-mediated mechanism. Journal of Experimental & Clinical Cancer Research 2022;41(1):90.
- Qu C, Li QP, Su ZR, Ip SP, Yuan QJ, Xie YL, Xu QQ, Yang W, Huang YF, Xian YF*, Lin ZX*. Nano-Honokiol Ameliorates the Cognitive Deficits in TgCRND8 Mice of Alzheimer’s Disease via Inhibiting Neuropathology and Modulating Gut Microbiota. Journal of Advanced Research 2021;35:231-43.
- Lin ZX*, Chan NHT, Kwan YK, Chan YT, Zhang H, Tam KYS, Lai MK, Lee CK, Ngan K, SYT, Lau YW, Xian XY, Ching J, Guo Y. A randomized controlled trial to assess the effectiveness and safety of acupuncture for overactive bladder: a study in Hong Kong population. Chinese Medicine 2020;15:108.
- Chen Y, Xian YF*, Loo S, Chan WY, Liu L, Lin ZX*. Anti-atopic dermatitis effects of Dictamni Cortex: studies on in vitro and in vivo experimental models. Phytomedicine 2021;82:153453.
- Yuan Q, Xian YF, Huang YF, Wu W, Song YQ, Lin ZX*. Intracisternal injection of beta-amyloid seeds promotes cerebral amyloid angiopathy. Brain Behavior and Immunity 2020;89:628-40.
- Xian Y, Zhang J, Bian Z, Zhou H, Zhang Z, Lin Z*, Xu H*. Bioactive Natural Compounds against Human Coronaviruses: A Review and Perspective. Acta Pharmaceutica Sinica B 2020;10(7):1163-1174.
- Li HQ, Ip SP, Yuan QJ, Tsim KKW, Dong TTX, Lin G, Han Y, Liu Y, Xian YF*, Lin ZX*. Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: studies in a transgenic mouse model of Alzheimer’s disease. Brain Behavior and Immununity 2019;82:264-278.
- Zhang X, Liu XD, Xian YF, Zhang F, Huang P, Tang Y, Yuan J, Lin ZX*. Berberine enhances survival and axonal regeneration of motoneurons following spinal root avulsion and re-implantation in rats. Free Radical Biology and Medicine 2019;143:454-470.
- Lau ST, Lin ZX*, Leung PS. Role of reactive oxygen species in brucein D-mediated p38 mitogen-activated protein kinase and nuclear factor-κB signaling pathways in human pancreatic adenocarcinoma cells. British Journal of Cancer. 2010;102(3):583-93.
- Lau ST, Lin ZX*, Liao YH, Zhao M, Cheng CHK, Leung PS. Brucein D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase. Cancer Letters. 2009;281(1):42-52.